Hydrastis canadensis, commonly known as goldenseal, is a perennial herb in the buttercup family, Ranunculaceae. It is native to southeastern Canada and the northeastern and central eastern United States, where it grows in shady, moist woodlands and forest clearings. The plant is characterized by its wrinkled rhizome, which is yellow-orange due to the presence of berberine and other isoquinoline alkaloids. Goldenseal has a long history of use in traditional medicine, particularly among Native American tribes, who used it for various ailments, including skin diseases, fever, and as a general tonic. In Hebrew, it is known as חלמונית קנדית, while in French it is called hydraste du Canada, and in German, kanadische gelbwurzel. The plant's rhizome and roots are primarily used for medicinal purposes, and it is often harvested from the wild, leading to concerns about its sustainability. Goldenseal is also known for its use as a natural dye and has been utilized in the food industry as a coloring agent.